Mapping the Antigenic Peptides of Sm26/2 in Glutathione S-Transferases of Schistosoma Mansoni

作     者：Jia Xi XU Meng Shen CAI(College of Chemistry and Molecular Engineering, Peking University, Beijing 100871 (School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083) 

作者机构：Peking Univ Coll Chem & Mol Engn Beijing 100871 Peoples R China Beijing Med Univ Sch Pharmaceut Sci Beijing 100083 Peoples R China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1998年第9卷第4期

页      面：377-379页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：schistosoma mansoni glutathione S-transferase antigenic peptide peptide vaccine 

摘      要：Six antigenic peptides of Sm26/2 glutathione S-transferase of schistosoma mansoni have been predicted according to their hydrophilicity, flexibility, accessibility, charge distribution and beta-turn in the secondary structure by the determination of its primary structure, and synthesized by solid phase method. Two of them showed good antigenicity by Dot-ELISA. They would be candidate peptides of synthetic anti-schistosomal vaccine.