Artificial simulated saliva,gastric and intestinal digestion and fermentation in vitro by human gut microbiota of intrapolysaccharide from Paecilomyces cicadae TJJ1213
Artificial simulated saliva, gastric and intestinal digestion and fermentation in vitro by human gut microbiota of intrapolysaccharide from Paecilomyces cicadae TJJ1213作者机构:College of Food Science and TechnologyNanjing Agricultural UniversityNanjing 210095China
出 版 物:《Food Science and Human Wellness》 (食品科学与人类健康(英文))
年 卷 期:2023年第12卷第2期
页 面:622-633页
核心收录:
学科分类:0832[工学-食品科学与工程(可授工学、农学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 083201[工学-食品科学]
基 金:co-financed by National Natural Science Foundation of China(U1903108,31871771 and 31571818) Natural Science Foundation of Jiangsu Province(BK20201320) Jiangsu Agriculture Science and Technology Innovation Fund(CX(20)3043) Postgraduate Research&Practice innovation Program of Jiangsu Province(KYCX19_0589) Qing Lan Project of Jiangsu Province and Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
主 题:Paecilomyces cicadae TJJ1213 Polysaccharide Fermentation Gut microbiota
摘 要:In this study,the in vitro digestion and fermentation of two intra-polysaccharide fractions(IPS1 and IPS2)from Paecilomyces cicadae TJJ1213 were *** constituent monosaccharides of IPS1 and IPS2 were not changed after simulated saliva,gastric and small intestinal ***,they can be hydrolyzed and utilized by gut microbiota,and short-chain fatty acids(SCFAs)level were increased after IPS1 and IPS2 ***,16 S r RNA sequencing analysis of fermentation samples were ***-diversity,beta-diversity and taxonomic composition differences analysis revealed that IPS1 and IPS2 promoted the proliferation of beneficial bacteria and modulated the overall structure of gut *** comparison analysis found that IPS1 increased the relative abundances of beneficial bacteria including Megamonas,Bifidobacterium and Lactobacillus,while IPS2 could increase the abundance of Bacteroides,Parabacteroides and *** addition,they can also decrease the levels of pathogenic bacteria containing Escherichia-Shigella,Klebsiella and *** results indicated that IPS from Paecilomyces cicadae TJJ1213 could be used as potential candidates for new functional foods.