Analysis of the successful clinical treatment of 140 patients with parathyroid adenoma:A retrospective study
作者机构：Department of Otorhinolaryngology Head and Neck SurgeryBeijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Department of Otorhinolaryngology and Head and Neck SurgeryPeking University First HospitalBeijing 100034China Department of Thyroid and Neck SurgeryBeijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2022年第10卷第28期
页 面：10031-10041页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Primary hyperparathyroidism Parathyroid adenoma Technetium-99m sestamibi SPECT/CT Surgical treatment Localization diagnosis Intraoperative parathyroid hormone monitoring
摘 要：BACKGROUND Parathyroid adenoma(PA) sometimes recurs after surgery,how to improve the surgical success rate of PA is the key to the treatment of this *** To investigate the clinical features,diagnosis,and surgical treatment of patients with *** Patients who were pathologically confirmed with PA and had undergone surgery for the first time between January 2010 and December 2017 at the Beijing Shijitan Hospital affiliated to Capital Medical University were included in the *** clinical features,localization diagnosis,and surgical treatment of these patients were *** Of the 140 patients,32 were male and 108 were female;132 cases had one adenoma,and 8 had two *** addition,114 cases had clinical symptoms,among which 51,28,23,8,and 4 had urinary system,skeletal system,digestive system,neuromuscular system,and neuropsychiatric symptoms,respectively,while 26 cases had no obvious *** median level of preoperative parathyroid hormone(PTH) was 201.0 pg/m *** positive detection rate of technetium-99m sestamibi(Tc-99m MIBI) single-photon emission computed tomography/computed tomography(SPECT/CT),ultrasound examination,and the combined use of Tc-99m MIBI SPECT/CT and ultrasound examination was 92.9%,85.5%,and 96.4%,*** surgery was performed in all patients,and PTH was monitored during *** success rate of surgery was 98.6%.After surgery,21 cases developed hypocalcemia,1 case developed temporary hoarseness,and 19 cases had transient hypoparathyroidism but there was no permanent hypoparathyroidism,postoperative hemorrhage,or hematoma in the surgical *** For patients with clinically unexplained skeletal system,urinary system,and neuropsychiatric symptoms,the possibility of PA should be *** examinations such as ultrasound and Tc-99m MIBI SPECT/CT could be integrated before surgery to obtain accurate localization *** preoperative localization,intraoperative PTH monitoring,an
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