2-Methoxyjuglone, a Promising Bioactive Compound for Pharmaceutical and Agricultural Purposes: A Review
作者机构：Department of PharmacyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China School of PharmacyTongji Medical CollegeHubei Key Laboratory of Natural Medicinal Chemistry and Resource EvaluationHuazhong University of Science and TechnologyWuhan430030China
出 版 物：《Current Medical Science》 (当代医学科学（英文）)
年 卷 期：2022年第42卷第5期
页 面：905-912页
核心收录：
学科分类：07[理学] 1001[医学-基础医学(可授医学、理学学位)] 070303[理学-有机化学] 0703[理学-化学]
基 金：supported by the National Natural Science Foundation of China(No.21572073 and No.3150010539).
主 题：2-methoxyjuglone bioactivities plant sources synthesis review
摘 要：2-Methoxyjuglone,a member of the 1,4-naphthoquinone family,was first obtained through semi-synthesis based on 2-hydroxyjuglone as the precursor in 1966.It has been isolated and identified from different plant species of the Juglandaceae,Sterculiaceae,and Proteaceae families.2-Methoxyjuglone has been demonstrated to possess a wide range of biological activities,including antitumor,antifungal,and antibacterial activities;in addition,it has been shown to poison fish and inhibit seed germination.These properties make 2-methoxyjuglone a promising bioactive compound for pharmaceutical and agricultural purposes.This review article provides an overview of the current research progress on 2-methoxyjuglone for the first time,with a primary focus on the plant sources,extraction,identification,synthesis,and biological activities associated with this compound for further development.
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