Pregnancy and Crohn’s disease:concerns and assurance of medical therapy

作     者：Reezwana Chowdhury Sunanda V.Kane 

作者机构：Division of Gastroenterology and HepatologyDepartment of MedicineJohns Hopkins UniversityBaltimoreMDUSA Division of Gastroenterology and HepatologyDepartment of MedicineMayo ClinicRochesterMNUSA 

出 版 物：《Gastroenterology Report》 (胃肠病学报道（英文）)

年 卷 期：2022年第10卷第1期

页      面：171-177页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Crohn’s disease pregnancy teratogenicity inflammatory bowel disease lactation biologics anti-TNF 

摘      要：Approximately 50%of patients with inflammatory bowel disease including both Crohn’s disease and ulcerative colitis are female with many being diagnosed and treated during their reproductive *** is important for women to be in remission prior to and during *** have been many advances in the treatment of inflammatory bowel disease,including new *** this review,we summarize the currently approved medications for Crohn’s disease and their safety in pregnancy and *** totality of evidence suggests that the majority of therapies are low-risk before and during pregnancy,and should be continued to control maternal disease.