Association between heart failure severity and mobility in geriatric patients: an in-clinic study with wearable sensors

作     者：Tobias Braun Anna Wiegard Johanna Geritz Clint Hansen Kim Eng Tan Hanna Hildesheim Jennifer Kudelka Corina Maetzler Julius Welzel Robbin Romijnders Walter Maetzler Philipp Bergmann Tobias Braun;Anna Wiegard;Johanna Geritz;Clint Hansen;Kim Eng Tan;Hanna Hildesheim;Jennifer Kudelka;Corina Maetzler;Julius Welzel;Robbin Romijnders;Walter Maetzler;Philipp Bergmann

作者机构：Department of NeurologyKiel UniversityArnold-Heller-Straße 324105 KielGermany Department of Internal Medicine IChristian-Albrechts-University of KielArnold-Heller-Straße 324105 KielGermany Department of Applied Health SciencesDivision of PhysiotherapyHochschule für Gesundheit(University of Applied Sciences)Gesundheits-campus 6-844801 BochumGermany HSD Hochschule Döpfer(University of Applied Sciences)Waidmarkt 3 und 950676 CologneGermany 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2022年第19卷第9期

页      面：660-674页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：severity wear limitations 

摘      要：BACKGROUND Individuals with heart failure(HF) frequently experience limitations in mobility, but specific aspects of these limitations are not well understood. This study investigated the association of HF severity, based on the New York Heart Association(NYHA) classes, with digital mobility outcomes(DMOs) and handgrip strength in older inpatients with *** For this explorative analysis, hospital admission and discharge data from an ongoing, prospective cohort study were used. The sample included older participants with HF and a sub-sample of heart-healthy individuals. Participants were equipped with a wearable inertial measurement unit(IMU) system during mobility performance(balancing, sit-to-stand transfer,walking). We analyzed the association between 17 DMOs and HF severity with multiple linear regression *** The total sample included 61 older participants(65–97 years of age, 55.7% female). Of all DMOs, only sway path in a semi-tandem stance position(m/s^(2)) showed a relevant association with NYHA classes(admission: β =-0.28, P = 0.09;discharge:β =-0.39, P = 0.02). Handgrip strength showed a trend towards a significant association(admission: β =-0.15, P = 0.10;discharge:β =-0.15, P = 0.19).CONCLUSIONS This is to our best knowledge the first analysis on the association of HF severity and IMU-based DMOs. Sway path and handgrip strength may be the most promising parameters for monitoring mobility aspects in treatment of HF.