Ultra-bright near-infrared-IIb emitting Zn-doped Ag_(2)Te quantum dots for noninvasive monitoring of traumatic brain injury

作     者：Yifei Zhou Biao Huang Shi-Hui Chen Shu-Lin Liu Mingxi Zhang Ran Cui Yifei Zhou;Biao Huang;Shi-Hui Chen;Shu-Lin Liu;Mingxi Zhang;Ran Cui

作者机构：College of Chemistry and Molecular SciencesWuhan UniversityWuhan 430072China State Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of TechnologyWuhan 430070China State Key Laboratory of Medicinal Chemical BiologyTianjin Key Laboratory of Biosensing and Molecular RecognitionResearch Centre for Analytical SciencesCollege of ChemistryNankai UniversityTianjin 300071China 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2023年第16卷第2期

页      面：2719-2727页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 070301[理学-无机化学] 

基　　金：supported by the National Natural Science Foundation of China(Nos.22174105 and 21974104) the National Key Research and Development(R&D)Program of China(No.2020YFA0908800) Large-scale Instrument and Equipment Sharing Foundation of Wuhan University 

主　　题：near-infrared-IIb(NIR-IIb)window silver telluride quantum dots fluorescence in vivo imaging 

摘      要：The long-wavelength region of the near-infrared-IIb(NIR-IIb,1,500–1,700 nm)imaging window has become an ideal window for in vivo imaging due to the suppressed photon scattering and near-zero autofluorescence of biological ***,it is necessary to develop fluorescent probes with excellent fluorescence performance and stability for NIR-IIb fluorescence *** this work,zinc-doped silver telluride quantum dots(Zn:Ag_(2)Te QDs)with bright fluorescence in the NIR-IIb window were *** introduction of Zn dopants inhibited crystal defects and reduced non-radiative ***,the quantum yield and fluorescence lifetime of Zn:Ag_(2)Te QDs were significantly *** addition,Zn-doping increased the number of ligands on the surface of QDs,thus enhancing the colloidal stability of Zn:Ag_(2)Te ***,the PEGylated Zn:Ag_(2)Te QDs with high absolute quantum yield realized noninvasive imaging of cerebral vascular of mouse with high resolution able to distinguish blood capillary,which could be utilized to monitor the brain condition of mice after traumatic brain injury.