Endovascular treatment for acute ischaemic stroke due to medium vessel occlusion:data from ANGEL-ACT registry

作     者：Dapeng Sun Raynald Xiaochuan Huo Baixue Jia Xu Tong Anxin Wang Gaoting Ma Ning Ma Feng Gao Dapeng Mo Zhongrong Miao 无 

作者机构：Department of Interventional NeuroradiologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of NeurologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of NeurosurgeryBeijing Fengtai You anmen HospitalBeijingChina China National Clinical Research Center for Neurological DiseasesBeijing Tiantan HospitalBeijingChina on behalf of the ANGEL-ACT Study Group 

出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)

年 卷 期：2023年第8卷第1期

页      面：51-58页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：the National Key Research and Development Program of China grant number 2016YFC1301500 

主　　题：acute occlusion treatment 

摘      要：Objectives To investigate the safety and efficacy of endovascular treatment(EVT)for acute medium vessel occlusion(MeVO)in the anterior circulation and to explore the independent predictors of the 90-day good outcome for such *** Data from ANGEL-ACT Registry were analysed in our *** outcomes,such as the modified Rankin Scale(mRS)at 90 days,successful recanalisation rate and symptomatic intracranial haemorrhage(SICH)rate,were compared between MeVO and acute large vessel occlusions(LVO).Then,the independent predictors of the good outcome at 90 days in MeVO patients were determined by the logistic regression *** We included 1032 subjects in the analysis,of which,147 were MeVO and 885 were *** at 90 days distribution(3(0-4)vs 3(0-5),common odds ratio(OR)=1.00,95%confidence interval(CI)0.73 to 1.38,p=0.994),SICH rate(4.8%vs 8.9%;OR=0.59,95%CI 0.26 to 1.34,p=0.205)and successful recanalisation rate(89.8%vs 89.7%;OR=1.0095%CI 0.51 to 1.93,p=0.992)were similar between the MeVO and LVO groups after adjusting for the *** identified that baseline neutrophil-to lymphocyte ratio≤4.1(OR=2.13,95%CI 1.14 to 3.99,p=0.019),baseline National Institutes of Health Stroke Scale≤14(OR=1.96,95%CI 1.02 to 3.80,p=0.045)and mechanical thrombectomy passes≤1(OR=2.16,95%CI 1.14 to 4.11,p=0.021)were independent predictors of the 90-day good outcome in MeVO patients undergoing *** Patients with MeVO achieved similar 90-day mRS,SICH rate and successful recanalisation rate after EVT compared with patients with *** independent predictors of 90-day good outcome in MeVO patients undergoing EVT were determined,which should be highly considered in MeVO stroke management.