Yak rumen microbiome elevates fiber degradation ability and alters rumen fermentation pattern to increase feed efficiency

作     者：Congcong Zhao Lamei Wang Shanlin Ke Xinhua Chen Akos Kenez Wei Xu Dangdang Wang Fan Zhang Yong Li Zhanhong Cui Yu Qiao Jing Wang Wenjuan Sun Jianhua Zhao Junhu Yao Zhongtang Yu Yangchun Cao Congcong Zhao;Lamei Wang;Shanlin Ke;Xinhua Chen;Akos Kenéz;Wei Xu;Dangdang Wang;Fan Zhang;Yong Li;Zhanhong Cui;Yu Qiao;Jing Wang;Wenjuan Sun;Jianhua Zhao;Junhu Yao;Zhongtang Yu;Yangchun Cao

作者机构：College of Animal Science and TechnologyNorthwest A&F UniversityYanglingShaanxiChina Division of GastroenterologyDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Channing Division of Network MedicineBrigham and Women's Hospital and Harvard Medical SchoolBostonMAUSA Department of Infectious Diseases and Public HealthCity University of Hong KongKowloonHong KongChina Qinghai Academy of Animal Husbandry and Veterinary SciencesQinghai UniversityXiningQinghaiChina Department Animal EngineeringYangling Vocational&Technical CollegeYanglingShaanxiChina Shanghai Majorbio Bio-pharm Technology Co.Ltd.ShanghaiChina Department of Animal SciencesThe Ohio State UniversityColumbusOHUnited States 

出 版 物：《Animal Nutrition》 (动物营养（英文版）)

年 卷 期：2022年第11卷第4期

页      面：201-214页

核心收录：

学科分类：0905[农学-畜牧学] 09[农学] 

基　　金：supported by the National Key Research and Development Projects of China the Shaanxi Provincial Key Research and Development Program 

主　　题：High plateau ruminant Rumen microbiome Metagenome Metabolome 

摘      要：Rumen microbes play an important role in ruminant energy supply and animal *** studies showed that yak(Bos grunniens)rumen microbiome and fermentation differ from other ***,little is understood about the features of the rumen microbiome that make yak adapted to their unique environmental and dietary *** study was to investigate the rumen microbiome and metabolome to understand how yak adapt to the coarse forage and harsh environment in the Qinghai-Tibetan *** female Qaidam yellow cattle(Bos taurus),9 dzomo(hybrids of cattle and yak)and 9 female plateau yak(***),about 5 to 6 years old,were used in this *** fermentation parameters,fibrolytic enzyme activities,and rumen metataxonomic were *** 18(6 samples per group)were selected for rumen metagenomic and metabolome *** analysis revealed that the rumen microbiota was significantly different among plateau yak,Qaidam yellow cattle,and dzomo(P0.05).Metagenomic analysis displayed a larger gene pool encoding a richer repertoire of carbohydrate-active enzymes in the rumen microbiome of plateau yak and dzomo than Qaidam yellow cattle(P0.05).Some of the genes encoding glycoside hydrolases that mediate the digestion of cellulose and hemicellulose were significantly enriched in the rumen of plateau yak than Qaidam yellow cattle,but glycoside hydrolase 57 that primarily includes amylases was abundant in Qaidam yellow cattle(P0.05).The rumen fermentation profile differed also,Qaidam yellow cattle having a higher molar proportion of acetate but a lower molar proportion of propionate than dzomo and plateau yak(P0.05).Based on metabolomic analysis,rumen microbial metabolic pathways and metabolites were *** metabolites are mainly amino acids,carboxylic acids,sugars,and bile *** in rumen microbial composition could explain the above *** present study showed that the rumen microbiome of plateau yak h