Awake prone positioning for patients with COVID-19-induced acute hypoxemic respiratory failure

作     者：Yonatan Perez Jian Luo Miguel Ibarra-Estrada Jie Li Stephan Ehrmann Yonatan Perez;Jian Luo;Miguel Ibarra-Estrada;Jie Li;Stephan Ehrmann

作者机构：Médecine Intensive RéanimationHôpital de HautepierreHôpitaux universitaires de StrasbourgStrasbourg 67000France Respiratory Medicine Unit and Oxford NIHR Biomedical Research CentreNDM Experimental MedicineUniversity of OxfordOxford OX39DUUK Unidad de Terapia IntensivaHospital Civil Fray Antonio Alcalde.Universidad de Guadalajara.GuadalajaraJalisco 44280Mexico Department of Cardiopulmonary SciencesDivision of Respiratory CareRush UniversityChicagoIL 60612USA Médecine Intensive RéanimationCIC 1415 INSERMCRICS-TriggerSep F-CRIN research networkCHRU de ToursTours France and Centre d’étude des pathologies respiratoires(CEPR)INSERM U1100Universitéde ToursTours 37000France 

出 版 物：《Journal of Intensive Medicine》 (重症医学（英文）)

年 卷 期：2022年第2卷第4期

页      面：233-240页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This research did not receive any specific grant from funding agencies in the public  commercial  or not-for-profit sectors 

主　　题：Respiratory distress syndrome Intensive care units Prone position Intubation 

摘      要：Whereas prone positioning of intubated patients suffering from acute respiratory distress syndrome represents the standard of care,proning non-intubated patients,so-called“awake prone positioning(APP),has only recently gained popularity and undergone scientific *** this review,we summarize current evidence on physiological and clinical effects of APP on patients’centered outcomes,such as intubation and mortality,the safety of the technique,factors and predictors of success,practical issues for optimal implementation,and future areas of *** evidence supports using APP among patients suffering from acute hypoxemic respiratory failure due to COVID-19 and undergoing advanced respiratory support,such as high-flow nasal cannula,in an intensive care unit *** teams should aim to prone patients at least 8 h *** research should focus on optimizing the tolerance of the technique and comprehensively evaluating benefits in other patient populations.