The outcome of ventricular septal defect combined with aortic regurgitation after surgical repair

作     者：MA Jian-rui WANG Xi-men ZHANG Shua LIU Xiao-bing WEN Shu-shen CHEN Ji-me ZHUANG Jian YUAN Hai-yu 马坚锐;王晰朦;张帅;刘晓冰;温树生;陈寄梅;庄建;袁海云

作者机构：Department of Cardiovascular SurgeryGuangdong Cardiovascular InstituteGuangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Department of EpidemiologyGuangdong Cardiovascular InstituteGuangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Shantou University Medical CollegeShantou 515041China 

出 版 物：《South China Journal of Cardiology》 (岭南心血管病杂志（英文版）)

年 卷 期：2022年第23卷第2期

页      面：162-168页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by the Project of Guangdong Provincial Clinical Research Center for Cardiovascular disease(No.2020B1111170011) Guangdong Special Funds for Science and Technology Innovation Strategy,China(Stability Support for Scientific Research Institutions Affiliated to Guangdong Province-GDCI 2021) Guangdong Peak Project(No.DFJH201802) 

主　　题：Ventricle septal defect Aortic regurgitation Aortic valve Aortic valvuloplasty Echocardiography 

摘      要：Objective:Ventricle septal defect(VSD)is commonly associated with aortic regurgitation and aortic leaflet prolapse due to anatomic and hemodynamic *** concomitant intervention of the aortic valve during VSD repair remains one of the major ***,little is known about the structure and hemodynamic change in the presence of postoperative progressive AR after VSD ***:From August 2012 to February 2019,VSD patients with aortic regurgitation who underwent VSD surgical repair with or without aortic valve intervention in our institution were retrospectively *** echo and postoperative echo in the followup were collected and ***:The mean age of the patients on VSD repair was *** with postoperative progressive aortic regurgitation showed significantly increased right atrium,mean pulmonary artery,valve flow velocity,and A-wave velocity,and significantly reduced right ventricle outflow tract and descending aorta flow velocity(P0.05).Additionally,compared with no AR intervention,aortic valvuloplasty during VSD repair predispose patients to have progressive AR(P0.05).Conclusion:There was augmented capacity in the right-heart system and increased valvular flow velocity in the left-heart system in VSD patients combined with postoperative *** aortic valvuloplasty or aortic valve replacement during surgical VSD repair might not be necessary,especially for those with no or mild AR *** valve replacement,if required,is a more appropriate alternative in halting postoperative AR progression than aortic valvuloplasty.