Treatment of gastric cancer with dermatomyositis as the initial symptom:Two case reports and review of literature
作者机构：Department of General SurgeryZhongshan HospitalFudan University School of MedicineShanghai 200032China
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2022年第10卷第27期
页 面：9727-9733页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by the National Natural Science Foundation of China No. 81773080
主 题：Gastric cancer Dermatomyositis Treatment Literature review Rash Case report
摘 要：BACKGROUND Dermatomyositis(DM) is a rare autoimmune disease involving the connective *** association between DM and gastric cancer remains *** with DM have an increased risk of cancer and higher *** requires immunosuppressive therapy,heightened surveillance,and immunologic response to internal *** SUMMARY Two cases of gastric cancer with DM as the first symptom in Zhongshan Hospital,Fudan University(Shanghai,China) were *** patients had a typical skin *** rash in the first patient involved mainly bilateral upper limbs and neck,while the second patient manifested rash associated mainly with the face,neck,and *** manifested muscle weakness in the extremities and elevated serum creatine *** resection of the tumor dramatically improved DMrelated symptoms in the two *** literature review showed that gastric cancer is more commonly associated with DM in middle-aged and older male *** The findings suggest the need for comprehensive screening for malignant tumors in patients with DM refractory to long-term pharmacotherapy or hormone manipulation.
维普期刊数据库