Nutritional assessment in patients with liver cirrhosis

作     者：Sara Haj Ali Awni Abu Sneineh Reem Hasweh 

作者机构：Department of Internal MedicineFaculty of MedicineAl-Balqa Applied UniversitySalt 19117Jordan Department of Gastroenterology and HepatologyUniversity of JordanFaculty of MedicineAmman 11942Jordan 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2022年第14卷第9期

页      面：1694-1703页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Malnutrition Cirrhosis Nutritional assessment Sarcopenia Nutrition Frailty 

摘      要：Malnutrition is a liver cirrhosis complication affecting more than 20%-50%of *** the term can refer to either nutrient deficiency or excess,it usually relates to undernutrition in cirrhosis *** is defined as limited physical function due to muscle weakness,whereas sarcopenia is defined as muscle mass loss and an advanced malnutrition *** pathogenesis of malnutrition in liver cirrhosis is multifactorial,including decreased oral intake,maldigestion/malabsorption,physical inactivity,hyperammonemia,hypermetabolism,altered macronutrient metabolism and gut microbiome *** with chronic liver disease with a Body Mass Index of18.5 kg/m2 and/or decompensated cirrhosis or Child-Pugh class C are at the highest risk of *** patients at risk of malnutrition,a detailed nutritional assessment is required,typically including a history and physical examination,laboratory testing,global assessment tools and body composition *** latter can be done using anthropometry,cross-sectional imaging including computed tomography or magnetic resonance,bioelectrical impedance analysis and dual-energy X-ray absorptiometry.A multidisciplinary team should screen for and treat malnutrition in patients with *** and sarcopenia are associated with an increased risk of complications and a poor prognosis in patients with liver cirrhosis;thus,it is critical to diagnose these conditions early and initiate the appropriate nutritional *** this review,we describe the prevalence and pathogenesis of malnutrition in liver cirrhosis patients and discuss the best diagnostic approach to nutritional assessment for them.