Non-alcoholic fatty liver disease:Is surgery the best current option and can novel endoscopy play a role in the future?
作者机构:Department of Gastroenterology and HepatologyGuys&St Thomas HospitalLondonSE17EHUnited Kingdom King’s College LondonSchool of Life Course SciencesFaculty of Life Sciences and MedicineLondon SE17EHUnited Kingdom
出 版 物:《World Journal of Hepatology》 (世界肝病学杂志(英文版)(电子版))
年 卷 期:2022年第14卷第9期
页 面:1704-1717页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:Obesity Metabolic associated fatty liver disease Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Bariatric endoscopy Bariatric surgery©The Author(s)2022.Published by Baishideng Publishing Group Inc.All rights reserved
摘 要:alcohol as the leading cause of cirrhosis in the Western *** remains to be a licensed pharmacological treatment for *** loss is advised for all patients with *** patients however,struggle to lose the recommended weight with lifestyle modification *** drugs have either failed to show significant improvement of steatosis or are poorly *** surgery has been shown to reduce liver steatosis and regress liver *** pathophysiology is not fully understood,however recent evidence has pointed towards changes in the gut microbiome following *** endoscopic treatment options provide a minimally invasive alternative for weight *** controlled trials are now required for further clarification.