Role of multiparametric magnetic resonance imaging in the diagnosis and staging of urinary bladder cancer

作     者：Essam A.Shalaby Ahmed R.Mohamed Tarek H.Elkammash Rasha T.Abouelkheir Ahmed M.Housseini 

作者机构：Department of UrologyFaculty of MedicineSuez Canal UniversityIsmailiaEgypt Department of Diagnostic RadiologyFaculty of MedicineSuez Canal UniversityIsmailiaEgypt Diagnostic RadiologyUrology and Nephrology CenterMansura UniversityMansuraEgypt 

出 版 物：《Current Urology》 (当代泌尿学（英文）)

年 卷 期：2022年第16卷第3期

页      面：127-135页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Apparent diffusion coefficient Bladder cancer Diffusion-weighted imaging Multiparametric magnetic resonance imaging Transurethral resection of bladder tumor 

摘      要：Objectives:To assess the role of multiparametric magnetic resonance imaging(mp-MRI)in the diagnosis and staging of urinary bladder cancer(BC).Materials and methods:Fifty patients diagnosed with bladder masses underwent mp-MRI *** results of 3 image sets were analyzed and compared with the histopathological results as a reference standard:T2-weighted image(T2WI)plus dynamic contrast-enhanced(DCE),T2WI plus diffusion-weighted images(DWI),and mp-MRI,including T2WI plus DWI and *** diagnostic accuracy of mp-MRI was evaluated using receiver operating characteristic curve ***:The accuracy of T2WI plus DCE for detecting muscle invasion of BC was 79.5%with a fair agreement with histopathological examination(κ=0.59);this percentage increased up to 88.6%using T2WI plus DWI,with good agreement with histopathological examination(κ=0.74),whereas mp-MRI had the highest overall accuracy(95.4%)and excellent agreement with histopathological data(κ=0.83).Multiparametric MRI can differentiate between low-and high-grade bladder tumors with a high sensitivity and specificity of 93.3%and 98.3%,***:Multiparametric MRI is an acceptable method for the preoperative detection and accurate staging of BC,with reasonable accuracy in differentiating between low-and high-grade BC.