Construction of axially chiral compounds via catalytic asymmetric radical reaction

作     者：Dong Liang Wenjing Xiao Sami Lakhdar Jiarong Chen 

作者机构：CCNU-uOttawa Joint Research CentreKey Laboratory of Pesticides&Chemical Biology Ministry of EducationCollege of ChemistryCentral China Normal UniversityWuhan 430079China CNRS/Universite Paul SabatierLaboratoire Heterochimie Fondamentale et AppliqueeToulouse 31062France 

出 版 物：《Green Synthesis and Catalysis》 (绿色合成与催化（英文）)

年 卷 期：2022年第3卷第3期

页      面：212-218页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the NationalNatural Science Foundation of China(Nos.21820102003,91956201,21901081,22171099) the Open Research Fund of the School of Chemistry and Chemical Engineering,the Henan Normal University(No.2021YB02) the Program of Introducing Talents of Discipline to Universities of China(No.B17019) the Excellent Doctoral DissertationCultivation Grant to D.L.from Central China Normal University(CCNU) 

主　　题：Axially chiral compounds Radical reactions Catalytic asymmetric synthesis Atropisomers Chiral allenes Photocatalysis 

摘      要：The chemistry of axially chiral compounds has emerged as a subject of increasing interest due to their widespread presence in natural products,bioactive molecules,advanced materials,and chiral ligands/*** the other hand,catalytic asymmetric radical-based transformations provide a complementary platform for the construction of enantiomerically enriched molecules that are in growing demand in the chemical and pharmaceutical *** recent years,considerable research efforts have been devoted to the development of catalytic asymmetric radical reactions for the construction of axially chiral compounds based on the unique reactivity modes of diverse *** this review,we critically illustrate these recent achievements according to different radical precursors and catalytic activation *** possible,special emphasis is also placed on the discussion of mechanistic features underlying these works and substrate *** review should be of great interest to the experts in this area,but also serve as a helpful starting point for new researchers in this field.