Advances in liquid biopsy in neuroblastoma
作者机构:Department of Pediatric SurgeryGuangzhou Institute of PediatricsGuangdong Provincial Key Laboratory of Research in Structural Birth Defect DiseaseGuangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhou 510623GuangdongChina Laboratory Animal CenterSchool of Chemical Biology and BiotechnologyPeking University Shenzhen Graduate SchoolShenzhen 518055China
出 版 物:《Fundamental Research》 (自然科学基础研究(英文版))
年 卷 期:2022年第2卷第6期
页 面:903-917页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金:the National Natural Science Foundation of China(82002636 82002635)
主 题:Liquid biopsy NB Diagnosis Application Cancer biomarker
摘 要:Even with intensive treatment of high-risk neuroblastoma(NB)patients,half of high-risk NB patients still *** therapies targeting the biological characteristics of NB have important clinical value for the personalized treatment of ***,the current biological markers for NB are mainly analyzed by tissue *** recent years,circulating biomarkers of NB based on liquid biopsy have attracted more and more *** review summarizes the analytes and methods for liquid biopsy of *** focus on the application of liquid biopsy in the diagnosis,prognosis assessment,and monitoring of ***,we discuss the prospects and challenges of liquid biopsy in NB.