Sodium selenite may be not the optimal speciation as an effective therapy for arsenic-induced anxiety-/depression-like behavior

作     者：Xiao-Hua Ren Xiao-Xuan Wang Lian-Ping He 

作者机构：School of MedicineTaizhou UniversityTaizhou 318000Zhejiang ProvinceChina 

出 版 物：《World Journal of Psychiatry》 (世界精神病学杂志)

年 卷 期：2022年第12卷第9期

页      面：1255-1257页

核心收录：

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

基　　金：Supported by Curriculum Reform Project of Taizhou University in 2021 No.xkg2021087 

主　　题：Depression Arsenic Major depressive disorder Sodium selenite Optimal speciation 

摘      要：Major depressive disorder is a serious and prevalent neuropsychiatric disorder,affecting more than 350 million people ***,sodium selenite(SS)was selected as the selenite supplement to improve the behavior in a mouse model of depression induced by *** may be not the optimal speciation for selenite supplementation and the source of the SS used in the study was not *** are many mouse models of depression and anxiety;however,in the current study,a classical mouse model of depression was not ***,several questions still need to be further *** together,the results indicate that SS may be not the optimal speciation as an effective therapy for As-induced anxiety-/depression-like behavior.