Microemulsion Synthesis of Mesoporous β-tricalcium Phosphate Powder with a Novel System

作     者：BIELEC Monikaq 黄岸 XIA Yuhao 戴红莲 BIELEC Monikaq;HUANG An;XIA Yuhao;DAI Honglian

作者机构：State Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of TechnologyShenzhen 5180ooChina Shenzhen Institute of Wuhan University of TechnologyWuhan 430070China 

出 版 物：《Journal of Wuhan University of Technology(Materials Science)》 (武汉理工大学学报（材料科学英文版）)

年 卷 期：2022年第37卷第4期

页      面：773-778页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 070205[理学-凝聚态物理] 0804[工学-仪器科学与技术] 0702[理学-物理学] 

基　　金：Funded by the National Natural Science Foundation of China(51772233) the Key Basic Research Program of Shenzhen(No.JCYJ20200109150218836)。 

主　　题：β-tricalcium phosphate mesoporous microemulsion bone marrow mesenchymal stem cells 

摘      要：The synthesis of mesoporous β-tricalcium phosphate(β-TCP)powder was performed by using the microemulsion approach,with hexadecyltrimethyl ammonium bromide(CTAB)/cyclohexane/n-octyl alcohol microemulsion system.The influences of different pH values and calcination temperatures on the phase composition of the β-TCP powder were studied.The in vitro proliferation of bone marrow mesenchymal stem cells(BMSCs)in the suspensions of β-TCP powders with meso-structure was studied.The phase composition,mesoporous structure,powder morphology,cell morphology and the optical density(OD)were characterized through X-ray diffraction(XRD),field emission scanning electron microscopy(FESEM),Fourier transform infrared(FTIR)spectroscopy,Nadsorption-desorption isotherms,inverted phase contrast microscopy and Multiskan spectrum,respectively.The mesoporous β-TCP powder with specific surface area of 12.85 m^(2)/g and the average pore size 7.11 nm was obtained through the microemulsion approach(100 g/L CTAB/250 mL/L cyclohexane/250 mL/L n-octyl alcohol)with a controlled pH of 7.0,after calcinating the powder at 800℃.It was confirmed that mesoporous β-TCP powder benefits the activity of BMSCs more than the non-mesoporous β-TCP powder.