New antibacterial depsidones from an ant-derived fungus Spiromastix ***-1

作     者：GUO Zhi-Kai HU Wen-Yong ZHAO Li-Xing CHEN Yan-Chi LI Sui-Jun CHENG Ping GE Hui-Ming TAN Ren-Xiang JIAO Rui-Hua GUO Zhi-Kai;ZHU Wen-Yong;ZHAO Li-Xing;CHEN Yan-Chi;LI Sui-Jun;CHENG Ping;GE Hui-Ming;TAN Ren-Xiang;JIAO Rui-Hua

作者机构：State Key Laboratory of Pharmaceutical BiotechnologyInstitute of Functional BiomoleculesSchool of Life SciencesNanjing UniversityNanjing 210093China Hainan Key Laboratory of Tropical Microbe ResourcesInstitute of Tropical Bioscience and BiotechnologyChinese Academy of Tropical Agricultural SciencesHaikou 571101China Yunnan Key Laboratory of Vaccine Research&Development on Severe Infectious DiseasesInstitute of Medical BiologyChinese Academy of Medical SciencesKunming 650118China Yunnan Institute of MicrobiologyYunnan UniversityKunming 650091China 

出 版 物：《Chinese Journal of Natural Medicines》 (中国天然药物（英文版）)

年 卷 期：2022年第20卷第8期

页      面：627-632页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the National Key Research and Development Programs(Nos.2018YFA0902000 and 2017YFC0506200) the National Natural Science Foundation of China(Nos.81991524 and 81673333) the Hainan Provincial Basic and Applied Basic Research Fund for High-Level Talents in Natural Science(Nos.2019RC306 and 2019RC352) the Central Public-interest Scientific Institution Basal Research Fund for CATAS-ITBB(Nos.1630052019011 and 1630052022016) 

主　　题：Fungus Spiromastix sp Depsidones Phytopathogenic bacteria Antibacterial 

摘      要：Six new(1–6)and seven known depsidones(7–13)were isolated from the culture of an ant(Monomorium chinensis)-derived fungus Spiromastix *** structures were elucidated by extensive spectroscopic analysis including high resolution MS,1D and 2D NMR *** new bromide depsidones were obtained through supplementing potassium bromide in the fermentation medium of Spiromastix *** isolated compounds showed various bioactivities against the tested phytopathogenic ***,new bromide compound 4,named spiromastixone S,exhibited the strongest activity against Xanthomonas oryzae *** with a MIC value of 5.2μmol·^L(−1).