Estimation of Iron Physiological Requirement in Chinese Children using Single Stable Isotope Tracer Technique
作者机构：Chinese Center for Disease Control and PreventionBeijing 102206China Gansu Center for Disease Control and PreventionGansu 73000LanzhouChina Key Laboratory of Trace Element NutritionMOHNational Institute for Nutrition and HealthChinese Center for Disease Control and PreventionBeijing 100050China National Institute of MetrologyBejing 100029China Department of General SurgeryPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBejing 100730China
出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)
年 卷 期：2022年第35卷第8期
页 面：681-687页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100403[医学-营养与食品卫生学] 10[医学]
基 金：supported by the National Natural Science Foundation of China [grant number 81330066]
主 题：Iron absorption rate Physiological requirement Chinese children Stale isotope tracer Dietary reference intakes
摘 要：Objective This study is to obtain precise data on iron physiological requirements in Chinese children using single stable isotope *** Thirty boys(10.6±0.2 years)and 27 girls(10.4±0.2 years)were received oral 6 mg ^(57)Fe each day for 5 consecutive *** blood samples were subsequently drawn to examine the change of total iron concentration and ^(57)Fe abundance at day 0,14,28,60,90,180,360,450,540,630,*** iron physiological requirement was calculated by iron loss combined with iron circulation rate once ^(57)Fe abundance stabilized in human *** The iron physiological requirement was significantly lower in boys than those values in girls(16.88±7.12 vs.18.40±8.81μg/kg per day,P0.05).Correspondingly,the values were calculated as 722.46±8.43μg/day for boys and 708.40±7.55μg/day for girls,*** nearly 10%iron absorption rate,the estimated average iron physiological requirement was 6.0 mg/day in boys and 6.2 mg/day in *** This study indicate that iron physiological requirement could require more daily iron intake in girls as compare with the values in boys having the same body *** findings would be facilitate to the new revised dietary reference intakes.
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