International patterns in incidence and mortality trends of pancreatic cancer in the last three decades: A joinpoint regression analysis

作     者：Irena Ilic Milena Ilic 

作者机构：Faculty of MedicineUniversity of BelgradeBelgrade 11000Serbia Department of EpidemiologyFaculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2022年第28卷第32期

页      面：4697-4714页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Ministry of Education Science and Technological development Republic of Serbia 2011-2020 No.175042 

主　　题：Pancreatic cancer Incidence Mortality Joinpoint analysis International pattern 

摘      要：BACKGROUND Pancreatic cancer,as the one of most fatal malignancies,remains a critical issue in the global burden of *** To estimate trends in pancreatic cancer incidence and mortality worldwide in the last three *** A descriptive epidemiological study was *** cancer incidence and mortality data were obtained from the database of the World Health *** of pancreatic cancer incidence and mortality during 2020 was *** age-standardized rates(ASRs,expressed per 100000)were *** estimate trends of incidence and mortality of pancreatic cancer,joinpoint regression analysis was used:the average annual percent change(AAPC)with the corresponding 95%confidence interval(95%CI)was ***,analysis was performed by sex and *** this paper,the trend analysis included only countries with high and medium data *** A total of 495773(262865 male and 232908 female)new cases and 466003(246840 male and 219163 female)deaths from pancreatic cancer were reported worldwide in *** both sexes,most of the new cases(191348;38.6%of the total)and deaths(182074;39.1%of the total)occurred in the Western Pacific *** both sexes,the highest ASRs were found in the European Region,while the lowest rates were reported in the South-East Asia *** general pattern of rising pancreatic cancer incidence and mortality was seen across countries worldwide in observed *** of all countries with an increase in pancreatic cancer incidence,females in France and India showed the most marked rise in incidence rates(AAPC=+3.9%and AAPC=+3.7%,respectively).Decreasing incidence trends for pancreatic cancer were observed in some countries,but without *** of all countries with an increase in pancreatic cancer mortality rates,Turkmenistan showed the most marked rise both in males(AAPC=+10.0%,95%CI:7.4–12.5)and females(AAPC=+6.4%,95%CI:3.5–9.5).The mortality trends of pancreatic cancer were decreasin