Effects of intravascular photobiomodulation on motor deficits and brain perfusion images in intractable myasthenia gravis: A case report
作者机构：School of MedicineNational Defense Medical CenterTaipei 114201Taiwan Department of Medical Education and ResearchKaohsiung Veterans General HospitalKaohsiung 813414Taiwan Department of Physical Medicine and RehabilitationKaohsiung Veterans General HospitalKaohsiung 813414Taiwan Department of Physical Medicine and RehabilitationTri-Service General HospitalTaipei 114202Taiwan
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2022年第10卷第24期
页 面：8718-8727页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
主 题：Myasthenia gravis Intravascular laser irradiation of blood Myasthenia gravisactivities of daily living scale Quantitative myasthenia gravis scale Single-photon emission computed tomography Case report
摘 要：BACKGROUND Myasthenia gravis(MG)is an autoimmune disorder caused by neuromuscular junction failure characterized by muscle weakness and *** herein report a case of MG that received intravascular laser irradiation of blood(ILIB)interventions and regained muscle power and better quality of *** our knowledge,no previous study has investigated the benefits of ILIB treatment on patients with *** also evaluated the changes in brain perfusion scan and the MG activities of daily living(MG-ADL)and quantitative MG(QMG)*** SUMMARY A 59-year-old man presented to our outpatient hospital experiencing ptosis,diplopia,fibromyalgia,muscle fatigue,and fluctuating weakness in his limbs for 1 *** on his history,physical examination,and laboratory investigations,the final diagnosis was a flare-up of MG with poor endurance and muscle *** patient agreed to receive *** single-photon emission computed tomography(SPECT)was performed both before and after ILIB *** receiving three courses of ILIB,the brain SPECT images showed greatly increased perfusion of the frontal lobe and anterior cingulate *** patient’s MG-ADL scale score decreased markedly from 17/24 to 3/*** QMG scale score also decreased remarkably from 32/39 to 9/*** symptoms of MG became barely detectable and the patient was able to perform his activities of daily living and regain muscle *** ILIB might have beneficial effects on MG,and brain SPECT images provided direct evidence of a positive correlation between ILIB and clinical performance.
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