Early diagnosis of pancreatic cancer:What strategies to avoid a foretold catastrophe
作者机构：Department of Medical and Surgical SciencesUniversity of BolognaBologna 40138Italy
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2022年第28卷第31期
页 面：4235-4248页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Pancreatic cancer Pancreatic ductal adenocarcinoma Early diagnosis Liquid biopsy Pancreatic cancer biomarkers Artificial intelligence Pancreatic cancer screening
摘 要：While great strides in improving survival rates have been made for most cancers in recent years,pancreatic ductal adenocarcinoma(PDAC)remains one of the solid tumors with the worst *** mortality often overlaps with *** resection is the only potentially curative treatment,but it can be performed in a very limited number of *** order to improve the prognosis of PDAC,there are ideally two possible ways:the discovery of new strategies or drugs that will make it possible to treat the tumor more successfully or an earlier diagnosis that will allow patients to be operated on at a less advanced *** aim of this review was to summarize all the possible strategies available today for the early diagnosis of PDAC and the paths that research needs to take to make this goal ever *** the most recent studies on risk factors and screening modalities,new laboratory tests including liquid biopsy,new imaging methods and possible applications of artificial intelligence and machine learning were reviewed and commented ***,in 2022 the results for this type of cancer still remain discouraging,while a catastrophic increase in cases is expected in the coming *** article was also written with the aim of highlighting the urgency of devoting more attention and resources to this pathology in order to reach a solution that seems more and more unreachable every day.
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