The molecular mechanisms that underlie neural network assembly
作者机构：Life Sciences Institute and Department of Cell and Developmental BiologyUniversity of Michigan210 Washtenaw AvenueRoom 5403Ann ArborMI 48109USA
出 版 物：《Medical Review》 (医学评论（英文）)
年 卷 期：2022年第2卷第3期
页 面：244-250页
学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学]
主 题：assembly development molecular mechanism neural network
摘 要：Neural networks are groups of interconnected neurons,which collectively give rise to emergent neural activities and functions that cannot be explained by the activity of single *** neural networks are assembled is poorly *** all aspects of neuronal development are essential for the assembly of a functional neural network,we know little about high-level principles that govern neural network assembly beyond the basic steps of neuronal *** this review,I use vertebrate spinal motor columns,Drosophila larval motor circuit,and the lamination in the vertebrate inner retina to highlight the spatial codes,temporal codes,and cell adhesion codes for neural network ***,these examples only show preliminary connections between neural network development and their *** needs to be done to understand the molecular mechanisms that underlie the assembly of functional neural networks.
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