Biocompatible Chemically Fueled Transient Polymer Nanoparticles for Temporally Programmable in Vivo Imaging

作     者：Chunyu Pan Jiajun Xu Liang Wang Yiyang Jia Jiahui Li Guancheng Liu Shoujun Zhu Bai Yang Yunfeng Li Chunyu Pan;Jiajun Xu;Liang Wang;Yiyang Jia;Jiahui Li;Guancheng Liu;Shoujun Zhu;Bai Yang;Yunfeng Li

作者机构：State Key Laboratory of Supramolecular Structure and MaterialsCollege of ChemistryJilin UniversityChangchun 130012 

出 版 物：《CCS Chemistry》 (中国化学会会刊（英文）)

年 卷 期：2023年第5卷第3期

页      面：669-681页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：This work was financially supported by the National Natural Science Foundation of China(NSFC)under grant no.21972054 

主　　题：polymer self-assembly nonequilibrium self-assembly polymer nanoparticles biocompatibility programmable bioimaging 

摘      要：Chemically fueled dissipative self-assembly paves the way for innovative materials with lifelike properties and *** of nonequilibrium systems with biocompatibility and biofunctions remains an important and challenging ***,we present biocompatible chemically fueled transient polymer nanoparticles and their applications in temporally programmable in vivo *** lifetime of the transient polymer nanoparticles can be tuned by varying the concentration of polymer,adenosine triphosphate,and ***,the transient assembly of polymer nanoparticles can be paused for storage and then subsequently *** transient polymer nanoparticles exhibit good ***,we implement in vivo imaging in a temporally programmable fashion by using an autonomous fluorescence modulator of transient nanoparticles assembled from polymers with a fluorescence *** results in this work provide a valuable way to achieve nonequilibrium self-assembly of synthetic systems with good biocompatibility and programmable biofunctions,accelerating innovative developments of nonequilibrium soft biomaterials.