Bipolar depression:a review of treatment options
作者机构：Psychiatry and Behavioral SciencesJohns Hopkins School of MedicineBaltimoreMarylandUSA
出 版 物：《General Psychiatry》 (综合精神医学（英文）)
年 卷 期：2022年第35卷第4期
页 面：230-239页
核心收录：
学科分类：0402[教育学-心理学(可授教育学、理学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100205[医学-精神病与精神卫生学] 1009[医学-特种医学] 10[医学]
摘 要：Bipolar depression(BD-D)is both common and incredibly challenging to *** treated individuals with BD-D experience depression approximately 19%of the time,and subsyndromal depression an additional 18%.This stands in clear contrast to the approximately 10%of time spent in hypomania and 1%of time spent in *** this high illness burden,there remain relatively few treatment options approved by the US Food and Drug Administration for *** the approved medications,four are second-generation antipsychotics(SGAs)and one is an SGA combined with an ***,particularly when used long-term,antipsychotics can pose a significant risk of adverse effects,raising the clinical conundrum of weighing the risks associated with longterm antipsychotic use versus the risk of relapse when patients are off ***,we review commonly used treatments for BD-D,including antipsychotics,classic mood stabilisers,electroconvulsive therapy and *** then address the somewhat controversial topic of antidepressant use in ***,we summarise emerging treatment options and highlight ongoing clinical *** hope this review will help compare the risks and benefits of several common and novel options for the treatment of patients with *** doing so,we also hope this review will aid the individualised selection of treatments based on each patient’s history and treatment goals.
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