抗Ma2相关性脑炎的早期病理学表现和长期改善

作     者：Blumenthal D.T. Salzman K.L. Digre K.B. J.Dalmau 郭俊 

作者机构：Dr.Department of NeurologySection Neuro-oncologyUniversity of Pennsylvania3 W.Gates3400 Spruce StreetPhiladelphiaPA 19104United States 

出 版 物：《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals.Clinical Neurology)

年 卷 期：2006年第12期

页      面：20-20页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：脑炎 Ma2 相关性 

摘      要：A 67-year-old man sequentially developed anti-Ma2-assoc-iated Paraneoplastic encephalitis(PNE)and contralateral herpes simplex encephalitis(HSE).Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells,B cells,and plasma *** T cells expressed the cytotoxic granule-associated protein TIA-1 and the membranolytic protein *** recovery was thought to be unlikely,treatment of the PNE with corticosteroids and resection of the associated lung cancer resulted in dramatic improvement for 21 months.