Construction of Customized Bio Incubator and Designing of Tailored Scaffolds for Bone Tissue Engineering from Laboratory Scale Up to Clinical Scale
作者机构：Department of PhysicsFaculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Materials ScienceInstitute of Graduate Studies and ResearchAlexandria UniversityAlexandriaEgypt
出 版 物：《Journal of Renewable Materials》 (可再生材料杂志（英文）)
年 卷 期：2022年第10卷第11期
页 面：2699-2716页
核心收录：
学科分类：1001[医学-基础医学(可授医学、理学学位)] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 10[医学]
主 题：Repairing segmental bone customized scaffolds stem cells designing bio incubator bone engineering
摘 要：In order to obtain larger,clinical-scale and practical-scale bone grafts,we have designed both tailored scaffolds and tailored bio incubator with optimal bio-production characteristics.Using DIC files to Simpleware Scan-IP(Simple-ware-exeter United Kingdom),we have digitally reconstructed segmental additive bone-tissue in order to perform images processing.Both hydroxyapatite and tannin composites have been used in order to get the final bone modules combined for retexturing of segmental bone defect.We have found that sectioning of bone segment deficiency reorganizations into well disk-shaped design permits one to standardize the cell culture and seeding protocol,to get better products.The present study concludes that some techniques with cultured cell in segmental bone grafts in the laboratory can be transferred and clinically used.
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