Specialized Microglia Resolve Neuropathic Pain in the Spinal Cord

作     者：Jing Yang Shulan Xie Shengmei Zhu Zhen-Zhong Xu 

作者机构：Department of Anesthesiology and Department of Neurobiology of the First Affiliated HospitalZhejiang University School of MedicineHangzhou310058China NHC and CAMS Key Laboratory of Medical NeurobiologyMOE Frontier Science Center for Brain Research and Brain–Machine IntegrationSchool of Brain Science and Brain MedicineZhejiang UniversityHangzhou310058China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2023年第39卷第1期

页      面：173-175页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

基　　金：This research highlight was supported by the National Key R&D Program of China(2021ZD0202703) Zhejiang Provincial Natural Science Foundation(LZ18C090002) the National Natural Science Foundation of China(81971050 and 82171206) 

主　　题：pain mechanisms Spinal 

摘      要：Neuropathic pain is a major health problem affecting up to 10%of the general population,resulting from a lesion or dysfunction of the somatosensory nervous system,including peripheral nerve injury(PNI)^([1]).However,neuropathic pain is difficult to treat because of its obscure *** types of neuropathic pain have been modelled in rodents to study its underlying mechanisms and identify novel therapeutic targets.