Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR):A critical overview on the most promising applications of molecular scissors in oral medicine
作者机构：Department of Basic Medical SciencesNeurosciences and Sense OrgansUniversity of Bari Aldo MoroBari74124Italy Department of Interdisciplinary MedicineUniversity of Bari Aldo MoroBari74124Italy Marrelli Health-Tecnologica Research InstituteBiomedical SectionStem Cells and Medical Genetics UnitsCrotone88900Italy Department of NeurosciencesReproductive and Odontostomatological SciencesUniversity of Naples Federico IINaples80131Italy
出 版 物：《BIOCELL》 (生物细胞（英文）)
年 卷 期：2022年第46卷第8期
页 面：1837-1842页
核心收录：
学科分类：0710[理学-生物学] 07[理学] 071007[理学-遗传学]
主 题：Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR) Dentistry Stem cells
摘 要：The scientific community is continuously working to translate the novel biomedical techniques into effective medical treatments.CRISPR-Cas9 system(Clustered Regularly Interspaced Short Palindromic Repeats-9),commonly known as the“molecular scissor,represents a recently developed biotechnology able to improve the quality and the efficacy of traditional treatments,related to several human diseases,such as chronic diseases,neurodegenerative pathologies and,interestingly,oral diseases.Of course,dental medicine has notably increased the use of biotechnologies to ensure modern and conservative approaches:in this landscape,the use of CRISPR-Cas9 system may speed and personalize the traditional therapies,ensuring a good predictability of clinical results.The aim of this critical overview is to provide evidence on CRISPR efficacy,taking into specific account its applications in oral medicine.
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