A dual-specific CRISPR-Cas nanosystem for precision therapeutic editing of liver disorders

作     者：Xiaojie Xu Honglin Tang Jjiajing Guo Huhu Xin Yuan Ping 

作者机构：College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Medical OncologySir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310058China Liangzhu LaboratoryZhejiang University Medical Center1369 West Wenyi RoadHangzhou 311121China 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2022年第7卷第9期

页      面：3198-3201页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：国家自然科学基金 

主　　题：acute liver disorders 

摘      要：Dear Editor,The most common liver disorders,such as acute liver injury and liver fbrosis,can induce acute or chronic inflammatory responses,which in turn gradually promote the development and progres-sion of the disorder.