Treating peripheral nerve injury-induced spinal cord degeneration and neuropathic pain with peripherally administrated stem cells

作     者：Zihui Wang Xiaofeng Jia Zihui Wang;Xiaofeng Jia

作者机构：Department of NeurosurgeryUniversity of Maryland School of Medicine Department of OrthopedicsAnatomy and NeurobiologyUniversity of Maryland School of Medicine Department of Biomedical EngineeringAnesthesiology and Critical Care MedicineJohns Hopkins University School of MedicineBaltimoreMDUSA 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第3期

页      面：537-538页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

基　　金：partially supported by R01NS117102 from the National Institutes of Health (NIH) Maryland Stem Cell Research Fund (2020-MSCRFD-5384), USA (both to XJ) 

主　　题：degeneration pain Morphological 

摘      要：Peripheral nerve injury(PNI)causes sensory and motor deficits as well as neuropathic pain,which seriously impacts patient quality of life(Jiang et al.,2017).Morphological and molecular changes in the spinal cord and dorsal root ganglia(DRG),such as neuronal cell death,nerve fiber degeneration,and glial activation,are strongly associated with PNI-induced pathological syndromes.