MEAN AND RANGE OF THE AMBULATORY PRESSUREIN NORMOTENSIVE SUBJECTS

作     者：J Staessen C Guo P De Cort R Fagard P Lijnen L Thijs R Van Hoof A Amery 

作者机构：Hypertension and Cardiovascular Rehabilitation Unit Department of Pathophysiology University of Leuven Belgium 

出 版 物：《中华医学杂志(英文版)》 (Chinese Medical Journal)

年 卷 期：1992年第105卷第4期

页      面：328-333页

核心收录：

主　　题：BLOOD-PRESSURE HYPERTENSION VALUES AGE 

摘      要：To perform a meta-analysis of published reportsin an attempt to determine the mean and range ofnormal ambulatory blood pressure(BP),23 studies in-cluding a total of 3 476 normal subjects werereviewed.Most studies were compatible with a mean24-h BP in the range of 115-120/70-75mmHg,amean day time BP of 120-125/75-80mmHg,and amean night time BP of 105 to 110/60 to 65 mmHg.With weighting for the number of subjects included inthe individual studies,the 24-h BP averaged 118/72mmHg,the day time BP 123/76 mmHg,and thenight time BP 106/64 mmHg.The night/day pres-sure ratio averaged 0.87 for systolic and 0.83 fordiastolic BP,with ranges across the individual studiesfrom 0.79 to 0.92 and from 0.75 to 0.90,respectively.If the mean ± 2 standard deviation interval in the va-rious studies was considered normal,the range ofnormality was on average 97 to 139/57 to 87 mmHgfor the 24-h BP,101 to 146/61 to 91 mmHg for theday time BP,and 86 to 127/48 to 79 mmHg for thenight time BP.Until the results of prospective studieson the relation between the ambulatory BP and the in-cidence of cardiovascular morbidity and mortality be-come available,the aforementioned intervals,whichsummarize the experience of 23 investigators,couldserve as a temporary reference for clinical practice.