A canine model of aortic arch aneurysm created with autologous pericardium

作     者：Weixiao Li Jun Li Qiang li Mingzhe Cui Rutao Xu Shuiting Zhai Cheshire Nick Tianxiao Li Jiangbo Chen Wenli Zhao Weixiao Li;Jun Li;Qiang li;Mingzhe Cui;Rutao Xu;Shuiting Zhai;Cheshire Nick;Tianxiao Li;Jiangbo Chen;Wenli Zhao

作者机构：Department of Vascular and Endovascular SurgeryZhengzhou University People's HospitalHenan Provincial Peoples HospitalZhenghouChina Operation DepartmentZhengzhou University People's HospitalHenan Provincial People's HospitalZhenghouChina Department of Medical ImagingZhengzhou University People's HospitalHenan Provincial People's HospitalZhenghouChina Department of Vascular SurgeryRoyal Brompton and Harefield HospitalLondonUK Department of Cerebrovascular DiseaseZhengzhou University People's HospitalHenan Provincial People's HospitalZhenghouChina 

出 版 物：《Journal of Interventional Medicine》 (介入医学杂志（英文）)

年 卷 期：2022年第5卷第3期

页      面：133-137页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by the Henan medical science and technology research projects(222102310014 and LGHJ20200058) 

主　　题：Aortic aneurysm Pericardium patch Ascending aorta Aortic arch Animal model 

摘      要：Background:To establish a canine model of aortic arch aneurysm that is suitable for research on new devices and techniques applied to the aortic *** and methods:Fifteen mongrel dogs underwent *** autologous pericardial patch was sewn on the aortotomy site in the anterior wall of the aortic *** animals were followed up for 3 months *** tomography angiography was used to visualize and measure the aneurysm *** and eosin staining was used to observe the histological characteristics of the aneurysm *** in aneurysm diameter over time were analyzed using analysis of ***:One dog died of hemorrhage during *** dogs survived the surgical *** of them died on the first postoperative day because of ruptures at the suturing *** diameter of the aneurysm model was twice as large as that of the aortic *** was no significant change in the maximum diameter of the aneurysm model during the follow-up ***:We established a controllable and stable aortic arch aneurysm model created with an autologous pericardium *** aneurysm model can be used to research endoleaks after thoracic endovascular aortic repair and new endovascular techniques can be applied to the aortic arch.