On demand CRISPR-mediated RNA N6-methyladenosine editing

作     者：Ying Xu Fu-Sen Liang 

作者机构：Department of ChemistryCase Western Reserve UniversityClevelandOH 44106USA 

出 版 物：《Genes & Diseases》 (基因与疾病（英文）)

年 卷 期：2022年第9卷第6期

页      面：1389-1390页

核心收录：

学科分类：08[工学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：This work is supported by National Institutes of Health(No.R21CA247638) 

主　　题：editing modification constitute 

摘      要：There are over 170 types of chemical modifications discovered across all the RNA categories in living organisms,1 which constitute the epitranscriptome.2 Emerging as an additional mechanism of post-transcriptional regulation of genetic information,these RNA modifications and the epitranscriptome have been tightly associated with the RNA fate and various human diseases.