Acute methanol poisoning with bilateral diffuse cerebral hemorrhage:A case report

作     者：Jin Li Zhi-Juan Feng Lei Liu Yu-Jie Ma 

作者机构：Department of Critical Care MedicineAir Force Medical CenterPLABeijing 100142China 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第19期

页      面：6571-6579页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：Acute methanol poisoning Cerebral hemorrhage Toxicity Hemodialysis Case report 

摘      要：BACKGROUND Acute methanol poisoning(AMP)is a systemic disease that mainly affects the central nervous system and is characterized by ocular damage and metabolic *** appropriate treatments are inadequate or delayed,the mortality can exceed 40%.As the most serious complication,cerebral hemorrhage is rare with reported prevalence of 7%-19%.CASE SUMMARY A 62-year-old man drank liquor mixed with 45%methanol and 35%*** vision blurred 10 h later and he fell into coma in another 9 *** toxicological tests were performed immediately,and continuous renal replacement therapy(CRRT)was carried out as the lactic acid exceeded 15 mmol/L and blood pH was *** addition,the toxicological report revealed 1300.5μg/mL of methanol in serum and 1500.2μg/mL in *** 59 h of CRRT,the methanol level decreased to 126.0μg/mL in serum and 151.0μg/mL in ***,the patient was still unconscious and his pupillary light reflex was *** tomography showed hemorrhage in the left *** 16 d of life support treatment,putamen hemorrhage developed into diffuse symmetric intracerebral *** the end,his family gave up and the patient was discharged,and died in a local *** Cerebral hemorrhage requires constant vigilance during the full course of treatment for severe cases of AMP.