Efficacy of Guhong injection versus Butylphthalide injection for mild ischemic stroke: A multicenter controlled study
作者机构：Department of NeurologyThe Seventh Medical Center of PLA General HospitalBeijing 100039China Department of NeurologyLiaoning Provincial People’s HospitalShenyang Liaoning Provincial People's HospitalShenyang 110016Liaoning ProvinceChina Department of NeurologyCangzhou City People’s HospitalCangzhou 061000Hebei ProvinceChina Department of NeurologyHuai’an Second People’s HospitalHuai’an 223002Jiangsu ProvinceChina Department of NeurologyGanyu People’s Hospital of LianyungangGanyu 222100Jiangsu ProvinceChina Department of NeurologyThe First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2022年第10卷第21期
页 面：7265-7274页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
主 题：Guhong injection Ischemic stroke Propensity score matching National Institutes of Health Stroke Scale
摘 要：BACKGROUND Most studies on Guhong injection have involved a single center with a small sample size,and the level of clinical evidence is *** To assess the safety and efficacy of Guhong injection for mild ischemic stroke(IS).METHODS A total of 399 IS patients treated at six hospitals from August 2018 to August 2019 were retrospectively *** patients were given Guhong injection(experimental group)or Butylphthalide injection(control group).Changes in National Institutes of Health Stroke Scale(NIHSS)and modified Rankin Scale(mRS)scores were observed before treatment and at 1,2,and 3 wk after treatment in each *** efficacy and safety of Guhong injection for IS were *** medications taken by the patients were confounding factors for efficacy *** factors were controlled by propensity score matching,and the results were further analyzed based on the *** The marked response rates at three follow-up visits were 64.64%,74.7%,and 66.7%in the experimental group,and 48.26%,45.4%,and 22.2%in the control *** marked response rates increased significantly in the experimental group compared with the control group(P0.05)and 64.0%and 47.7%in the control group(P0.05)at the first
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