Structural diversity and biological activity of natural p-terphenyls
作者机构：Key Laboratory of Marine DrugsSchool of Medicine and PharmacyChinese Ministry of EducationOcean University of ChinaQingdao266003China Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and TechnologyQingdao266237China
出 版 物：《Marine Life Science & Technology》 (海洋生命科学与技术（英文）)
年 卷 期：2022年第4卷第1期
页 面：62-73页
核心收录：
学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 07[理学] 070303[理学-有机化学] 0703[理学-化学] 0836[工学-生物工程]
基 金：supported by the NSFC-Shandong Joint Fund(U1906212,U1606403) the Pilot National Laboratory for Marine Science and Technology(2018SDKJ0401-2,2016ASKJ08-02) the National Natural Science Foundation of China Major Project for Discovery of New Leading Compounds(81991522) the National Science and Technology Major Project for Significant New Drugs Development(2018ZX09735004) the Major National Science and Technology Projects of the Ministry of Science and Technology(81991522) the Fundamental Research Funds for the Central Universities(201941001) Project funded by China Postdoctoral Science Foundation(2017M622286) the Taishan Scholar Youth Expert Program in Shandong Province(tsqn201812021).
主 题：p-Terphenyl Marine organism Structure Biological activity Cytotoxic
摘 要：p-Terphenyls are aromatic compounds consisting of a central benzene ring substituted with two phenyl groups,and they are mainly isolated from terrestrial and marine organisms.The central ring of p-Terphenyls is usually modified into more oxidized forms,e.g.,para quinone and phenols.In some cases,additional ring systems were observed on the terphenyl-type core structure or between two benzene moieties.p-Terphenyls have been reported to have cytotoxic,antimicrobial,antioxidant andα-glucosidase inhibitory effects.In this review,we will mainly summarize the structural diversity and biological activity of naturally occurring p-Terphenyls referring to the research works published before.
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