The Impact of Different Stain Carriers on the mRNA Profiling from Bloodstains

作     者：Hemiao Zhao Qingluan Lin Qi Zhang Jing Chen Zheng Tu Ruiqin Yang Lan Hu Chong Wang 

作者机构：Division of Forensic GeneticsKey Laboratory of Forensic GeneticsInstitute of Forensic ScienceMinistry of Public Security Qionghai Police BureauHainan ProvinceChina School of Crime InvestigationChinese People's Public Security UniversityBeijing 

出 版 物：《Journal of Forensic Science and Medicine》 (法庭科学与法医学杂志（英文）)

年 卷 期：2022年第8卷第2期

页      面：76-79页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：This study is funded by the basic research fund of the central public welfare research institute (2020JB001) 

主　　题：Bloodstains mRNA profiling stain carrier 

摘      要：Unlike DNA profiling,mRNA profiling is greatly affected by external *** analyze the influence of different stain carriers on the detectability of mRNA markers from bloodstains,this study examined 10 carriers,including a knife,cotton swab,paper,plastic,leather,cement,chopsticks,clothes,ceramic block,and *** detecting five specific mRNA markers(HBA,HBB,ALAS2,GYPA,and SPTB)and the housekeeping gene B2M in peripheral blood samples,no statistically significant differences in the effects of the carriers were *** results suggest that when performing mRNA testing on bloodstains,the effect of the stain carrier has little influence.