Efficacy of Shugan Hewei Therapy for Chronic Atrophic Gastritis:A Systematic Review and Meta-Analysis

作     者：Jing-Bin Niu Xiao Gai De-Cai Yang Yi-Xin Zheng Yang Cao Chun-Mei Zhu Peng Qian Hai-Xia Yan Hua-Ling Song Guo-Ping Liu Jing-Bin Niu;Xiao Gai;De-Cai Yang;Yi-Xin Zheng;Yang Cao;Chun-Mei Zhu;Peng Qian;Hai-Xia Yan;Hua-Ling Song;Guo-Ping Liu

作者机构：School of Basic Medical SciencesShanghai University of Traditional Chinese MedicineShanghai 201203China School of Public HealthShanghai University of Traditional Chinese MedicineShanghai 201203China 

出 版 物：《Chinese Medicine and Culture》 (中医药文化（英文）)

年 卷 期：2022年第5卷第2期

页      面：97-109页

学科分类：100506[医学-中医内科学] 1006[医学-中西医结合] 1005[医学-中医学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：This study was financed by grants from the National Natural Science Foundation of China(No.81873236,81270050) the Key Laboratory of Health Identification and Assessment in Shanghai(No.13DZ2261000) 

主　　题：Chinese herbal medicine Chronic atrophic gastritis Efficacy Meta-analysis Shugan Hewei therapy 

摘      要：Objective:Shugan Hewei therapy(SHT)acts to soothe the liver and harmonize the *** is a classical traditional Chinese medicine method widely used in China to treat chronic atrophic gastritis(CAG)due to liver qi invading the ***,the clinical effects of SHT remain *** aimed to evaluate the overall clinical effective rate and safety of SHT in treating ***:We used the Jadad scale and Cochrane Collaboration risk of bias tool to evaluate the methodological quality of studies investigating *** medical databases were searched to identify relevant *** data extraction and quality evaluation,27 randomized controlled trials,including 2,441 patients,were considered eligible for *** serious heterogeneity or publication bias was observed across the included *** used Revman 5.3 statistical software to evaluate the general clinical effective rate and safety of ***:The results showed that SHT was more effective(RR=1.25;95%CI[1.20,1.29];P0.01)and safer(MD=0.24,95%CI[0.08,0.75];P0.01)than control interventions comprising western medicine,Chinese patent medicine,and/or western medicine+Chinese patent *** with the control interventions,SHT resulted in greater improvements in the symptom scores for stomach distension and stomachache,serum gastrin level,histopathologic changes,Helicobacter pylori(HP)inhibition rate,and gastric mucosal ***:SHT was more effective and safer than control interventions for CAG.