The development of molecular and nano actinide decorporation agents

作     者：Xiaomei Wang Cen Shi Jingwen Guan Yemeng Chen Yigong Xu Juan Diwu Shuao Wang Xiaomei Wang;Cen Shi;Jingwen Guan;Yemeng Chen;Yigong Xu;Juan Diwu;Shuao Wang

作者机构：State Key Laboratory of Radiation Medicine and ProtectionSchool for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2022年第33卷第7期

页      面：3395-3404页

核心收录：

学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.21976127,U2167222,21790370,22106116) the Natural Science Foundation of Jiangsu Province(No.BK20190044,BK20210736) funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD) China Postdoctoral Science Foundation(No.2020M681716) 

主　　题：Actinides Chelator Binding selectivity Coordination mode Decorporation efficiency 

摘      要：Internal contamination of actinides has led to significant health hazards to the public and workers in the context of nuclear power plant accidents,uranium ore mining,and reprocessing of the used *** effective sequestering agent that is able to remove accidentally incorporated actinides in vivo with low toxicity is always in urgent *** molecular decorporation ligands have been the most widely researched agents for the past few decades,while preliminary studies of functionalized nanoparticles have shown their clear advantages in metal binding selectivity,toxicity,and oxidative stress ***,the state-of-the-art of those two types of decorporation agents is presented with special attention being paid on the correlation between the solution and solid-state chemistry of those agents with actinides and the corresponding decorporation efficacies.