Stereoselective construction of atropisomers featuring a C-N chiral axis

作     者：Yong-Jie Wu Gang Liao Bing-Feng Shi 

作者机构：Center of Chemistry for Frontier TechnologiesDepartment of ChemistryZhejiang UniversityHangzhou 310027China Green Catalysis CenterCollege of ChemistryZhengzhou UniversityZhengzhou 450001China Department of ChemistryNational University of SingaporeSingapore 117543Singapore School of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiang 453007China 

出 版 物：《Green Synthesis and Catalysis》 (绿色合成与催化（英文）)

年 卷 期：2022年第3卷第2期

页      面：117-136页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Financial support from the National Natural Science Foundation of China(Nos.21925109 and 21772170) the Open Research Fund of School Chemistry and Chemical Engineering,Henan Normal University and the Center of Chemistry for Frontier Technologies of Zhejiang University is gratefully acknowledged 

主　　题：Atropisomers C-N Chiral axis Asymmetric synthesis Stereoselectivity 

摘      要：Atropisomeric C-N compounds belong to an important class of axially chiral ***,whereas the asymmetric synthesis of biaryl atropisomers have been well established,general and efficient strategies to access single enantiomers of C-N atropisomers are still *** recently,innovative methods have been developed,providing new opportunities for the highly stereoselective synthesis of this vital class of ***,we comprehensively summarize the development in this emerging field and give some insights into future *** is placed on the synthetic strategies.