Endoscopic Bariatric and Metabolic Therapies for Liver Disease:Mechanisms,Benefits,and Associated Risks

作     者：Mengting Ren Xinxin Zhou Lu Lv Feng Ji 

作者机构：Department of GastroenterologyThe First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2022年第10卷第5期

页      面：986-994页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported in part by a grant from the Key Research and Development Program of Zhejiang Province(No.2019C03031) 

主　　题：Weight loss Endoscopy Obesity Nonalcoholic fatty liver disease Liver transplantation Liver abscess 

摘      要：Nonalcoholic fatty liver disease(NAFLD),including advancedstage nonalcoholic steatohepatitis(NASH),is currently the most common chronic liver disease worldwide and is projected to become the leading indication for liver transplantation(LT).However,there are no effective pharmacological therapies for *** bariatric and metabolic therapies(EBMTs)are less invasive procedures for the treatment of obesity and its metabolic *** recent studies have demonstrated the beneficial effects of EBMTs on NAFLD/*** this review,we summarize the major EBMTs and their mechanisms of *** further discuss the current evidence on the efficacy and safety of EBMTs in people with NAFLD/NASH and obese cirrhotic LT *** potential utility of EBMTs in reducing liver volume and perioperative complications in bariatric surgery candidates is also ***,we review the development of liver abscesses as a common serious adverse event in duodenaljejunal bypass liner implantation.