From Fluorescent Probes to the Theranostics Platform
作者机构：State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsShanghai Engineering Research Center of Nano-Biomaterials and Regenerative MedicineCollege of ChemistryChemical Engineering and BiotechnologyDonghua UniversityShanghai201620 China Department of ChemistryFudan UniversityShanghai200438 China
出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)
年 卷 期：2022年第40卷第16期
页 面：1964-1974页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 10[医学]
基 金：the financial support from the Fundamental Research Funds for the Central Universities(2232021A-06) the National Natural Science Foundation of China(21877013,22007012,22177019) the Shanghai Sailing Program(20YF1401100)
主 题：Fluorescent probes Imaging agents Prodrugs Theranostics platform Nanoparticles
摘 要：Since the advent of fluorescent probes,they have been widely used in the field of life *** probes can not only light up the cells,tissues and organs,but also be used to explore the bio-distribution of specific types of disease ***,the development of new fluorescent probes capable of recognition of bio-markers is extremely important for the diagnosis of the related ***,we focus on our recent works experienced the evolution from the beginning of simply fluorescent probes to the construction of theranostics *** have developed a series of new fluorescent probes for the detecting and imaging of reactive oxygen species(ROS)and specific enzymes in vitro and in living *** the shift of the fluorescence signal from visible to near-infrared region,we expanded the application of the fluorescent probes from in vitro to in *** recently,we further constructed theranostics platforms to combine the diagnosis immediately with the corresponding treatment.
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