Shining the spotlight on NMR metabolic profiling and bioactivities of different solvent extracts of Piliostigma thonningii

作     者：Kouadio Ibrahime Sinan Gokhan Zengin Antonio Fiorentino Chiara Vuotto Mohamad Fawzi Mahomoodally Sharmeen Jugreet Jasmina Glamočlija Marina Soković Ouattara Katinan Etienne Catarina Guerreiro Pereira Luísa Custódio Kannan R.R.Rengasamy Brigida D'Abrosca 

作者机构：Department of BiologyScience FacultySelcuk UniversityKonyaTurkey Dipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche –DiSTABiFUniversità degli Studi della Campania “Luigi Vanvitelli”via Vivaldi 43 I-81100CasertaItaly Department of Health SciencesFaculty of Medicine and Health SciencesUniversity of MauritiusRéduit80837Mauritius Laboratory of MycologyDepartment of Plant PhysiologyInstitute for Biological Research “Siniša Stanković”National Institute of Republic of SerbiaUniversity of BelgradeBelgradeSerbia Laboratoire de BotaniqueUFR BiosciencesUniversité Félix Houphouët-BoignyAbidjanCote d'Ivoire Centre of Marine SciencesUniversity of AlgarveCampus de Gambelas8005-139FaroPortugal Centre for Transdisciplinary ResearchDepartment of PharmacologySaveetha Dental CollegeSaveetha Institute of Medical and Technical Sciences (SIMATS)Chennai600077India 

出 版 物：《Food Bioscience》 (食品生物科学（英文）)

年 卷 期：2022年第47卷第3期

页      面：1337-1350页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 08[工学] 083201[工学-食品科学] 

主　　题：Piliostigma thonningii Bioactivities Enzyme inhibitors Antioxidants Antimicrobial NMR Metabolic profiling 

摘      要：Piliostigma thonningii (Fabaceae) is a versatile medicinal plant used as a traditional remedy,especially in African *** the present study,ethyl acetate,methanolic and water extracts of different parts of (fruits,leaves,stem barks) *** were evaluated for their bioactive contents,enzyme inhibitory,antioxidant and antimicrobial *** potentials were also displayed in various methods like phosphomolybdenum assay (0.79–5.94 mmol TE/g),radical scavenging assays (DPPH:20.39–471.28 mg TE/g;ABTS:42.43–654.14 mg TE/g);reducing assays (CUPRAC:102.98–1207.42 mg TE/g;FRAP:45.30–656.25 mg TE/g) and metal chelating activity (2.55–22.32 mg EDTAE/g).In particular,the methanolic and water extracts showed better antioxidant *** for a few,the extracts were also found to act as inhibitors of enzymes such as acetylcholinesterase (2.35–5.35 mg GALAE/g),butyrylcholinesterase (0.83–13.80 mg GALAE/g),tyrosinase (4.03–143.86 mg KAE/g),amylase (0.21–1.39 mmol ACAE/g) and glucosidase (3.52–7.13 mmol ACAE/g).Additionally,all the tested extracts possessed significant antibacterial (minimum inhibitory concentration (MIC) and minimum bactericidal concentration:0.11–0.61 mg/ml) and antifungal (MIC and minimum fungicidal concentration:0.04–0.61 mg/ml) ***,the data garnered from the present study provides a bright scope for the advanced investigation on this particular plant possessing pharmacologically active traits.