Clinical study of warm needling moxibustion combined with entecavir in the treatment of compensated cirrhosis due to chronic hepatitis B

作     者：NIE Lu ZHANG Juanli 聂璐;张娟丽;孔谐和(Translator)

作者机构：Hubei Provincial Hospital of TCMWuhan 430060China 

出 版 物：《Journal of Acupuncture and Tuina Science》 (针灸推拿医学（英文版）)

年 卷 期：2022年第20卷第3期

页      面：199-205页

核心收录：

学科分类：1005[医学-中医学] 1002[医学-临床医学] 100512[医学-针灸推拿学] 10[医学] 

主　　题：Acupuncture-moxibustion Therapy Warm Needling Therapy Acupuncture Medication Combined Entecavir Hepatitis B Chronic Liver Cirrhosis Liver Function Tests 

摘      要：Objective:To investigate the efficacy and possible mechanism of action of warm needling moxibustion combined with entecavir in the treatment of compensated cirrhosis due to chronic hepatitis B(CHB).Methods:Ninety patients were randomly divided into a control group and an observation group,with 45 patients in each *** control group was given oral entecavir,and the observation group was given additional warm needling *** serum alanine transaminase(ALT),aspartate transaminase(AST),albumin(ALB)levels,portal vein internal diameter,splenic vein internal diameter,spleen thickness,and liver hardness were compared before and after *** serum hyaluronic acid(HA),laminin(LN),procollagen typeⅢ(PCⅢ),typeⅣcollagen(Ⅳ-C),interleukin(IL)-21,and platelet-derived growth factor(PDGF)levels were also ***:After treatment,the serum ALT and AST levels decreased(P0.05);in the observation group,the serum IL-21 and PDGF levels decreased significantly(P0.05)and were lower than those in the control group(P0.05).Conclusion:Warm needling moxibustion combined with entecavir treatment can improve liver function,reduce the inner diameters of the portal vein and splenic vein,spleen thickness,and liver hardness,and improve liver fibrosis indicators in pa