Breast cancer screening and early diagnosis in Chinese women

作     者：Rui Ding Yi Xiao Miao Mo Ying Zheng Yi-Zhou Jiang Zhi-Ming Shao Rui Ding;Yi Xiao;Miao Mo;Ying Zheng;Yi-Zhou Jiang;Zhi-Ming Shao

作者机构：Key Laboratory of Breast Cancer in ShanghaiDepartment of Breast SurgeryFudan University Shanghai Cancer CenterShanghai 200032China Department of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China Department of Cancer PreventionFudan University Shanghai Cancer CenterDepartment of OncologyShanghai Medical CollegeFudan UniversityShanghai 200032China Precision Cancer Medicine CenterFudan University Shanghai Cancer CenterShanghai 200032China 

出 版 物：《Cancer Biology & Medicine》 (癌症生物学与医学（英文版）)

年 卷 期：2022年第19卷第4期

页      面：450-467页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 10[医学] 

基　　金：This work was supported by Grants from the National Key R&D Project of China(Grant No.2020YFA0112304) the National Natural Science Foundation of China(Grant Nos.91959207,92159301 and 82002792) the Shanghai Key Laboratory of Breast Cancer(Grant No.12DZ2260100) the Shanghai Key Clinical Specialty of Oncology(Grant No.shslczdzk02001) the Clinical Research Plan of SHDC(Grant Nos.SHDC2020CR4002 and SHDC2020CR5005) the Shanghai Sailing Program(Grant No.20YF1408600). 

主　　题：Breast cancer screening Chinese imaging screening genetic test 

摘      要：Breast cancer is the most common malignant tumor in Chinese women,and its incidence is increasing.Regular screening is an effective method for early tumor detection and improving patient prognosis.In this review,we analyze the epidemiological changes and risk factors associated with breast cancer in China and describe the establishment of a screening strategy suitable for Chinese women.Chinese patients with breast cancer tend to be younger than Western patients and to have denser breasts.Therefore,the age of initial screening in Chinese women should be earlier,and the importance of screening with a combination of ultrasound and mammography is stressed.Moreover,Chinese patients with breast cancers have several ancestry-specific genetic features,and aiding in the determination of genetic screening strategies for identifying high-risk populations.On the basis of current studies,we summarize the development of risk-stratified breast cancer screening guidelines for Chinese women and describe the significant improvement in the prognosis of patients with breast cancer in China.