Current status of human adenovirus infection in China
作者机构：NHC Key Laboratory of Medical Virology and Viral DiseasesWHO WPRO Regional Reference Laboratory of Measles and RubellaChinese Center for Disease Control and PreventionMeasles Laboratory in National Institute for Viral Disease Control and Prevention155#Changbai RoadChangping DistrictBeijing 102206China
出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)
年 卷 期：2022年第18卷第8期
页 面：533-537页
核心收录：
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
基 金：Key Public Health Projects of the National Health Commission(ZDGW21-131031103000180005) The Key Technologies R&D Program of the Ministry of Science and Technology(2018ZX10713002)
主 题：Acute respiratory tract infections Conjunctivitis Gastroenteritis Human adenovirus Hepatitis Unknown etiology
摘 要：Background Outbreaks of severe,acute hepatitis among children have recently attracted global *** pathogen causing the outbreak remains unknown,but there is growing evidence that it may be associated with human adenovirus(HAdV).Data sources A review of adenovirus-related clinical studies,epidemiological studies,etiological studies,and case reports was conducted by reviewers *** HAdV can cause a wide variety of clinical *** the Mainland of China,HAdV infection accounts for 5.8%–13%of patients with acute respiratory infections,and these infections are mainly caused by species B,C,and E of *** acute conjunctivitis,39.8%–74.9%of sporadic cases were infected by B and D species of *** of keratoconjunctivitis and pharyngoconjunctival fever related to HAdV infection could be found throughout the *** pediatric patients with acute gastroenteritis,HAdV-41 was the predominant HAdV type,followed by HAdV species B and *** types of HAdV,including HAdV-5,HAdV-7,HAdV-1,and HAdV-2,have previously been reported as potential pathogens associated with HAdV hepatitis in immunocompromised ***,few HAdV-related hepatitis cases have been reported in China to *** There are no systematic surveillance and clinical studies on HAdV hepatitis in ***,it is imperative to establish a nationwide HAdV virological surveillance system to collect relevant clinical,epidemiological and virological surveillance data and risk factor information as soon as possible to assess the potential risk of HAdV hepatitis among children.
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