Potential of extracellular vesicles and exosomes as diagnostic markers for cholangiocarcinoma

作     者：Linping Cao Jiawei Hong Jian Wu 

作者机构：Division of Hepatobiliary and Pancreatic SurgeryDepartment of SurgeryFirst Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouChina Key Lab of Combined Multi-Organ TransplantationMinistry of Public HealthHangzhouChina 

出 版 物：《Hepatobiliary Surgery and Nutrition》 (肝胆外科与营养（英文）)

年 卷 期：2022年第11卷第3期

页      面：436-438页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：the Natural Science Foundation of Zhejiang Province(LQ21H160025) 

主　　题：diagnosis epithelium malignancy 

摘      要：Cholangiocarcinoma(CCA),a malignant carcinoma originating from biliary epithelium,is the second largest primary liver malignancy,accounting for 10-15%of hepatobiliary ***,CCA is a fatal malignancy,with a 5-year survival rate of less than 10%(1).The lack of typical symptoms and signs makes early CCA difficult to identify and diagnose by early health *** diagnosis of CCA mainly relies on radiography,tumor biomarkers,invasive diagnosis,as well as pathological examination,which results in the majority of patients being detected in the middle and late stages,and only about one-third of CCA patients have access to treatment(1).